| No | Name | Team | G | PA | AB | R | H | 2B | 3B | HR | RBI | HBP | BB | SO | SacB | SacF | SB | CS | AVG | OBP | SLG | OPS |
| 18 | Sailer, Brock | Drones | 5 | 16 | 15 | 4 | 6 | 1 | 3 | 1 | 1 | 3 | .400 | .400 | .467 | .867 | ||||||
| 25 | Scherbenske, Drew | Drones | 1 | 4 | 3 | 2 | 1 | 1 | 1 | .000 | .250 | .000 | .250 | |||||||||
| 23 | Scholer, Pat | Reds30 | 4 | 14 | 12 | 5 | 7 | 4 | 2 | 1 | .583 | .643 | .583 | 1.226 | ||||||||
| 23 | Scholer, Pat | Wildcats | 15 | 54 | 45 | 17 | 17 | 11 | 2 | 7 | 3 | 8 | .378 | .481 | .378 | .859 | ||||||
| 3 | Scholer, Will | Reds30 | 18 | 65 | 50 | 19 | 18 | 3 | 11 | 4 | 10 | 8 | 1 | 4 | .360 | .492 | .420 | .912 | ||||
| Schoonover, Brandon | Thunder18 | 6 | 9 | 8 | 3 | 1 | 2 | 1 | 3 | 1 | .125 | .222 | .125 | .347 | ||||||||
| 35 | Schueller, Brian | Saints | 13 | 41 | 31 | 13 | 13 | 2 | 9 | 2 | 8 | 3 | .419 | .561 | .484 | 1.045 | ||||||
| 16 | Schulze, Nick | Heat | 9 | 19 | 18 | 2 | 3 | 1 | 1 | 10 | .167 | .211 | .167 | .377 | ||||||||
| 21 | See, Ethan | Red Sox | 11 | 14 | 11 | 1 | 3 | 9 | .000 | .214 | .000 | .214 | ||||||||||
| 7 | Seeliger, Scott | Saints | 13 | 36 | 34 | 7 | 9 | 2 | 7 | 2 | 4 | .265 | .306 | .324 | .629 | |||||||
| 15 | Sefrit, Jarek | Thunder30 | 7 | 14 | 10 | 2 | 2 | 2 | 4 | 3 | .200 | .429 | .200 | .629 | ||||||||
| 14 | Seiler, Marv | Yankees | 12 | .000 | .000 | .000 | .000 | |||||||||||||||
| 21 | Seiler, Marv | Grays | 13 | 42 | 36 | 13 | 12 | 6 | 2 | 4 | 1 | .333 | .429 | .333 | .762 | |||||||
| 6 | Serrano, Marving | Reds30 | 16 | 59 | 51 | 21 | 24 | 2 | 1 | 12 | 1 | 6 | 8 | 1 | 11 | .471 | .525 | .549 | 1.074 | |||
| 08 | Sherman, Jeff | Blues48 | 1 | 1 | 1 | 3 | .000 | .000 | .000 | .000 | ||||||||||||
| 17 | Sickels, Jalen | Oaks | 4 | 5 | 5 | 2 | .000 | .000 | .000 | .000 | ||||||||||||
| 50 | Silva, Roy | Saints | 10 | 29 | 26 | 3 | 9 | 1 | 3 | 3 | 3 | 3 | 2 | .346 | .414 | .385 | .798 | |||||
| 50 | Silva, Roy | Demons | 1 | 2 | 1 | 2 | .000 | 1.000 | .000 | 1.000 | ||||||||||||
| Silva, Roy | Yankees | 9 | .000 | .000 | .000 | .000 | ||||||||||||||||
| 7 | Sinclair, James | Twins | 12 | 44 | 37 | 17 | 13 | 2 | 8 | 1 | 6 | 7 | 5 | .351 | .455 | .405 | .860 | |||||
| 15 | Sittig, Brian | Blues48 | 3 | 12 | 11 | 3 | 7 | 1 | 4 | 1 | 3 | 1 | .636 | .667 | .909 | 1.576 | ||||||
| Skinner, Jordan | Twisters | 7 | 16 | 14 | 5 | 4 | 1 | 1 | 2 | 2 | .286 | .375 | .357 | .732 | ||||||||
| 14 | Slavin, Dennis | Twins | 7 | 21 | 18 | 5 | 6 | 4 | 3 | .333 | .429 | .333 | .762 | |||||||||
| 77 | Slings, Doug | Heat | 3 | 9 | 9 | 1 | 3 | 3 | 1 | .333 | .333 | .333 | .667 | |||||||||
| 22 | Sloth, Ryan | Blues48 | 8 | 25 | 21 | 7 | 11 | 2 | 2 | 2 | 1 | 4 | 2 | .524 | .600 | .524 | 1.124 |